Rontgen Result Of Caries Molar In White Rat (Rattus Novergicus) With Treatment Of Herbal Tooth Paste (Pluchea Indica Leaves Extract)

Nungki Fatimatuzzahra, Fitriana Rahayu, Nourmalita Safitri Ningsih, Feny Feny, Adam Darsono, Siti Isrina Oktavia Salasia


Dental caries is an infectious disease resulting email and dentin demineralization. Dental caries have relation with consumption of cariogenic food. But, dental caries also can be initiation with bacteria from Streptococcus class like Streptococcus mutans. Beluntas leaves (Pluchea indica L.) are a tropical herbal plant and this plant very easy to find and spread in Asia-Pacific areas. This plant is reported contain of anti-inflammation substance and decrease of necrosis in ventriculus, neutralization of snake toxin, antioxidants, antiulcerative, hepatoprotective, antimoeba, and broad spectrum of antimicrobial. The purpose of this research is to know differential Rontgen of caries molar in white rat (Rattus norvegicus) after treatment by herbal tooth paste of Pluchea indica leaves. First weeks of research, molar rat‘s induced by Streptococcus mutans and given by caries diet. In 9th and 10th weeks group 1 given 40% Pluchea indica leaves extract paste, group 2 given 50% Pluchea indica leaves extract paste, group 3 given 60% Pluchea indica leaves extract paste. After that, rats were necropsy and collected the pathological changes by Rontgen. Based on rontgen result, there was a difference of contrasting colors and shows the difference between the experimental groups. Results of Rontgen show there are differences in the color analysis especially in group 2 (50% Pluchea indica leaves extract paste) and shown similarity to the negative control group. This happen because of Pluchea indica extract paste can reduce amount of bacteria that

initiated dental caries. 

Full Text:



Ardiansyah, L. Nuraida dan N. Andarwulan. 2003. Aktivitas Antimikroba Ekstrak Daun Beluntas (Pluchea indica L.) dan Stabilitas Aktivitasnya pada Berbagai Konsentrasi Gram dan Tingkat pH. Jurnal Teknologi dan Industri Pangan. 16(2):90-97

Bagramian, R.A; F.G. Godoy; A.R. Volpe. 2009. The global increase in dental caries. A pending public health crisis. American Journal of Dentistry, Vol. 21, No. 1, February, 2009.

Bisignano, G.; Sanogo, R.; Marino, A.; Aquino, R.; D'Angelo, V.; Germano, M.P.; De Pasquale, R. and Pizza C. 2000. Antimicrobial activity of Mitracarpus scaber extract and isolated constituents. Letter Appl. Microb. 30: 105-108.

Chambers, S. 2012. Public Health and Dental Caries in Young Children in Deprived Communities in Scotland. Electronically Published SUMJ †003. 2012 Scottish Universities Medical Journal, Dundee. Published online: May 2012.

Harris, R; A.D. Nicoll; P.M. Adair; C.M. Pine. 2004. Risk factors for dental caries in young children: a systematic review of the literature. Community Dental Health (2004) 21 (Supplement), 71–85.

Kabir, F., Katayama, S., Tanji, N., Nakamura, S. 2014. Antimicrobial Effects of Chlorogenic Acid and Related Compounds. J Korean Soc Appl Biol Chem. Vol 57(3), 359−365

Nishina, A.K.; Kinaichi, H.; Uchibori, T.; Seino, H. and Osawa T. 1991. 2,6-dimethoxy-p-benzequinone as an antimicrobial subtance in the bark of Phyllostachys heterocycla var. Pubscens a species of thick- stemmed bamboo. J Agric Food Chem 39: 266-269.

Ozdemir, D. 2014. Dental caries and preventive strategies. journal of educational and instructional studies in the world. November 2014, Volume: 4 Issue: 4 Article: 04 ISSN: 2146-7463.

Sakanaka, S., Kim, M., Taniguchi, M., and Yamamoto, T. 1989. Antibacterial substances in Japanese green tea extract against Streptococcus mutans, a cariogenic bacterium. Agric Biol Chem 53 (9): 2307- 2311.

Soeharto, I. 2002. Pencegahan dan Penyembuhan Penyakit Jantung Koroner. Jakarta: PT Gramedia Pustaka Utama.

Suriyaphan, O. 2014. Nutrition, Health Benefits and Applications of Pluchea indica (L.) Less Leaves. Mahidol University Journal of Pharmaceutical Sciences 2014; 41 (4), 1-10

Utami, Prapti, dan Puspaningtyas, D. Ervira. 2013. The Miracle of Herbs. Jakarta Selatan: PT Agromedia Pustaka.

Winarno, M.W. and D. Sundari. 1988. Pemanfaatan Tumbuhan sebagai Obat Diare di Indonesia. Cermin Dunia Kedokteran. 109:25-32.


  • There are currently no refbacks.