Fluoride Release Of Dental Sealants Following Exposure To Fluoride Toothpaste And Fluoride Varnish

Khandakar Nuruzzaman, Siriruk Nakornchai, Rudee Surarit


Background: Application of dental sealants on pit and fissure areas is an effective intervention to prevent and reduce development of dental caries. Fluoride incorporation into dental sealants increases potency on caries reduction. Fluoride exposure of dental sealant from different sources is expected to enhance fluoride release from dental sealants.

Objective: The study was aimed to compare fluoride release from different dental sealants following exposure to fluoride toothpaste and fluoride varnish.

Methods: Three types of dental sealants were included: Group A- glass ionomer sealant (GIS); Group B- resin sealant and Group C- giomer sealant. Thirty specimens of each material were prepared using stainless steel mold (10Å~2 mm) and stored in plastic container containing artificial saliva. Initial fluoride release was measured by a specific fluoride electrode every 24 hours for 15 days. The saliva was changed after each measurement. At day 15th, the specimens were randomly divided into 3 subgroups (n=10) and exposed to following regimens; subgroup A- fluoride toothpaste (1000 ppm) twice daily, subgroup B- fluoride varnish (22,600 ppm) once only at day 15th and subgroup C- control group; not exposed to any fluoride regimens. Fluoride release after fluoride exposure was measured for another 15 days. Data were analyzed using one way ANOVA and Games-Howell post hoc test at a significance level of 0.05.

Results: GIS released highest amount of fluoride (42.9±1.91ppm) at the first 15 days followed by giomer sealant (27.79±1.66 ppm) and resin sealant (1.31±0.11 ppm) and showed significantly different among groups (p=0.00). Fluoride toothpaste increases fluoride release from all tested dental sealants while showed superior efficacy on giomer sealant followed by GIS and resin sealant (p=0.00). Fluoride varnish application promotes fluoride release significantly higher in all tested sealants (p=0.00).

Conclusions: Daily exposure of fluoride toothpaste and single application of fluoride varnish enhances fluoride release of all dental sealants.

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