The Factor Risk of Obesity to Asthma and Intervention Study of Treatment Technique: A Systemic Review

Febrina Yolanda, Jaslis Ilyas

Abstract


Asthma has increased by 2.0 and 2.3 times in obese children and adults. Obesity is also associated with inflammation and control of asthma which can be mediated by increased respiratory tract inflammation and hyper responsive respiratory tract. Systematic Review and meta-analysis method by using PRISMA- P 2015 were used in this study. We were collected through searching electronic literature from Sciencedirect, Researchgate and Google Scholar. Based on the literature study method conducted in 25 related journals, it can be summarized that there are similar perceptions of the results of analysis where asthma is closely related to obesity due to several main factors. Obesity impact as an important role in the development of respiratory diseases. Asthma and obesity are complex and multifactorial which greatly affects health conditions, where the body's internal factors and environment play an important role in the health and quality of life of the community. Weight loss can improve lung function, reduce the possibility of asthma, and improve overall health status. Appropriate treatment techniques for individuals suffering from acid obesity can be done through simvastatin therapy and increased body adiponectin.


Full Text:

PDF

References


X. Song, B. Li, H. Wang, X. Zou, R. Gao, W. Zhang, T. Shu, H. Zhao, B. Liu, J. Wang. Asthma alleviates obesity in males through regulating metabolism and energy expenditure. BBA - Molecular Basis of Disease. (2019) 350–359.

L.Guilleminault. Chronic cough and obesity. Pulmonary Pharmacology & Therapeutics. Vol 55 (2019) 84– 88.

J.A. Lucas, S. Moonie, M.B. Hogan, W.N. Evans. Efficacy of an exercise intervention among children with comorbid asthma and obesity. Public Health Vol 159 (2018) 123- 128.

A. Jeong, P.O. Bridevaux, M. Imboden, S. Hansen, E. Zemp, N. Probst-Hensch, G. Lovison, C. Schindler. Heterogeneity of obesity-asthma association disentangled by latent class analysis, the SAPALDIA cohort. Respiratory Medicine. Vol 125 (2017) 25-32.

H. M. Nurrizki , O. kadarulah. The Effect of Obesity to the Occurrence of Asthma in Fatimah Islamic Hospital Cilacap, Indonesia. Sainteks vol

Y. Tomita, H. Hayashi, Y. Fukutomi, M. Irie, K. Azekawa, C. Okada, Y. Kamide, K. Sekiya, Y. Nakamura, T. Shimoda, Y. Hasegawa, M. Taniguchi. Obesity, but not metabolic syndrome, as a risk factor for late-onset asthma in Japanese women. Allergology International. Vol 68 (2019) 240-246.

M.To, K. Haruki, A. Hitani, Y. Kono, N. Honda, I. Kano, Y. To. Obesity-associated severe asthma in an adult Japanese population. Respiratory investigation. Vol 56 (2018) 440–447

R. Barros, A. Moreira, P. Padrao, V.H. Teixeira, P. Carvalho, L. Delgado, A. Moreira. Obesity increases the prevalence and the incidence of asthma and worsens asthma severity. Clinical Nutrition. Vol 36 (2017) 1068-1074.

H. Nagase. Severe asthma in Japan. Allergology International. Vol 68 (2019) 167-171.

L. Zhu, X. Chen, L. Chong, L. Kong, S. Wen, H. Zhang, W. Zhang, C. Li. Adiponectin alleviates exacerbation of airway inflammation and oxidative stress in obesity-related asthma mice partly

through AMPK signaling pathway. International Immunopharmacology. Vol 67 (2019) 396–407.

U. Peters, PhD, A.E. Dixon, MA. B.M. BCh, E. Forno, MD, MPH. Obesity and asthma. Journal of Allergy

and Clinical immunology. Vol 141 (2018) 1169–1179.

H.Tashiro, S.A. Shore. Obesity and severe asthma. Allergology International. Vol 68 (2019) 135-142.

W. Han, J. Li, H. Tang, L. Sun.Treatment of obese asthma in a mouse model by simvastatin is associated

with improving dyslipidemia and decreasing leptin level. Biochemical and Biophysical Research

Communications (2017) 1-7.

C.T. Juel, C.S. Ulrik. Obesity and asthma. Impact on Severity, Asthma Control, And Response To Therapy,

Respir. Care. Vol 58 (2013) 867–873.

Gibeon D, Batuwita K, Osmond M, Heaney LG, Brightling C, Niven R, Mansur A, Chaudhuri R, Bucknall

CE, Rowe A, Guo Y, Bhavsar PK, Chung KF, Menzies-Gow. Obesity-Associated Severe Asthma

Represents a Distinct Clinical Phenotype. Original Research Asthma. Vol 10 (2013) 407-414.

V. Hjellvik, A. Tverdal and K. Furu. Body Mass Index as Predictor for Asthma: A Cohort Study Of 118,723

Males and Females. European Respiratory Journal. Vol 35 (2014) 1235–1242

E. Rand Sutherland. Linking obesity and asthma. New York Academy of Sciences. Vol. 1311 (2014) 31–

Ahmadizar F, Vijverberg SJ, Arets HG, de Boer A, Lang JE, Kattan M, Palmer CN, Mukhopadhyay S,

Turner S, Maitland-van der Zee AH. Childhood obesity in relation to poor asthma control and

exacerbation: a meta-analysis. European Respiratory Journal. Vol 48(2016):1063-1073

Ostrom NK, Parsons JP, Eid NS, Craig TJ, Stoloff S, Hayden ML, et al. Exercise induced bronchospasm,

asthma control, and obesity. Allergy Asthma Proceeding. Vol. 34(2013):342-348.

Van Leeuwen JC, Hoogstrate M, Duiverman EJ, Thio BJ. Effects of dietary induced weight loss on exercise- induced bronchoconstriction in overweight and obese children. Pediatr Pulmonol. Vol.49(2014) 55-

Chen Z, Salam MT, Alderete TL, Habre R, Bastain TM, Berhane K, et al. Effects of childhood asthma on

the development of obesity among school-aged children. Am J Respir Crit Care Med. Vol.19 (2017)

-8.

Westergren T, Fegran L, Nilsen T, Haraldstad K, Kittang OB, Berntsen. Active play exercise intervention

children with asthma. A pilot study. Vol 16 (2016)


Refbacks

  • There are currently no refbacks.