What is the most effective intervention to improve medication adherence among type 2 diabetics?: a systematic review

Nadia Putri Maretta, Prastuti Soewondo


Most type 2 diabetics do not adhere to their medication. The aim of this study is to review the intervention in improving medication adherence among type 2 diabetics. The authors performed a systematic review with analyzing Randomized Controlled Trials studies from 3 database sources including PubMed, Scopus, and Springer Link. From 11 selected studies, health education with personal face to face interaction between diabetics and health worker is the most effective intervention to improve medication adherence. Five studies with personal face to face health education as the intervention show significant changes in medication adherence (p<0,05) and a significant change in HbA1C level (p<0,05). With personal interaction, health workers could give suitable education based on personal barriers to adhere their medication. However, improving medication adherence was not always followed by changing at diabetics HbA1C level. Other treatments are needed to lower HbA1C level beside management of pharmacotherapy.

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